Preparation of Core Particles for Aqueous Film Coating Using Agitation Fluidized Bed.

Granulation of core particles suitable for film coating by agitation fluidized bed II. A proposal of a rapid dissolution test for evaluation of bitter taste of ibuprofen.

To prepare powdered drugs that do not have a bitter taste, a film coating covering the surfaces of the core particles is required. The dissolution rate of ibuprofen from the coated particles changes according to the physical properties of the core particles. In this study, the effects of the physical properties of granules prepared by using several scales of agitation fluidized beds on the drug...

Aerodynamics of a Fluidized Bed of Forestry Biomass Particles with Mechanical Agitation

The aerodynamic behavior of wet forestry biomass particles mechanically shaken in a fluidized bed was analyzed with turning velocity between 0.5 and 2 r.p.s. It was concluded that the agitation exerts an important effect on the fluidization of wet biomass particles. The effect of the agitator is not relevant if the particles have low humidity content. In addition, a methodology based on the Erg...

Experimental Study of Coating in a Bottom Sprayed Fluidized Bed

Several investigations have been devoted towards understanding the coating process in fluidized beds. Most of these studies focused on spraying liquid droplets over the bed. However, due to the complexity of these systems, more investigations are still required to quantify the effect of operating conditions on the coating criteria. The present work aims at fundamentally understanding and pr...

24 Fixed Film Stationary Bed and Fluidized Bed Reactors

A Review on Aqueous Film Coating Technology

Until about 1950, sugar coating was the first choice as coating agent for pharmaceutical preparation and much time & efforts were spent in perfecting the sugar coating techniques. Nobody ever was concerned about the problems like material cost, toxic effect due to coating or pollution etc. because the solvent used was always water. However, sugar coating technique was time consuming, affecting ...